Upset Thursday continued as Serb Janko Tipsarevic eliminated American Andy Roddick by posting a hard fought four set victory getting the better of the No.6 seed in a fourth set tiebreak 7-4 to capture the last three sets for a big upset win into Round Three.

It was another disappointment for the former two-time runner-up who was hoping to make a big run and possibly meet Rafael Nadal in the semis and Roger Federer in the final. Instead, he’ll pack his bags and have to regroup preparing for the hard court season with the U.S. Open Series next month before the final grand slam of the year here in Flushing Meadows.

In watching that fourth set closely, the difference was Tipsarevic’s backhand which produced at least 15 more winners from that side than Andy’s. There were a couple of key moments late during extended rallies which Roddick made the wrong choice in where the 24 year-old talented Serb flattened it out a la Marat Safin going down the line for big winners.

If there was a game which summed up the level of frustration for the Roddick camp, it had to be the 10th game of the set when Tipsarevic couldn’t make a first serve and practically handed him the fourth on a silver platter. But on two break points, Andy couldn’t even make him play a ball coming up with awful returns which didn’t come close. Sadly, he tanked. There’s no other way to put it. These were not hard second serves. His indecisiveness cost him.

He also blew a third set point in the 12th game allowing his opponent to get into the breaker where he completed a 6-7 (5), 7-5, 6-5, 7-6 (4) win advancing to a third round meeting against Russian Dmitry Tursunov.

From our vantage point, Roddick’s tactics and not his will were the reason he lost today. At times, he didn’t use the right plays during pivotal moments. Whether it was going the wrong way right into a backhand reply down the line or missing a return because he couldn’t decide whether to chip and charge or stay back, he just didn’t make the right choices.

Andy always gives his best on the court. If he improved tactically, he could win another major. The clock is ticking.

His beautiful fiancee SI swimsuit model Brooklyn Decker sure looked concerned. Maybe she can tell him what he’s doing wrong before it’s too late.

Nadal advanced to Round Three with a four set win over hard server Ernest Gulbis 5-7, 6-2, 7-6 (2), 6-3.

Also avoiding the upset bug was defending women’s champion Venus Williams who was a straight set winner. Tenth seeded Slovakian stunner Daniela Hantuchova wasn’t as fortunate falling in three to Russian Alisa Kleybanova (try pronouncing that a few times) 6-3, 4-6, 6-1.

One thing you can conclude is that players who had injuries and missed the French haven’t performed well in London as both Roddick and Hantuchova were out and didn’t have much match play coming into Wimbledon. Though in Andy’s case, he did reach the semis at Queen’s Club before losing a competitive match to Nadal.

I definitely think having matches underneath your belt helps. Especially on a surface players aren’t used to due to how brief the grasscourt season is.

Veteran former champ Lindsay Davenport withdrew from her second round match against Gisela Dulko due to a bad knee.

We’ll have more on Wimbledon later.